The effects of cashew nut intake on lipid profile and blood pressure: a systematic review and meta-analysis of randomized controlled trials

Jalali, Mohammad, Karamizadeh, Maliheh, Ferns, Gordon A, Zare, Morteza, Moosavian, Seyedeh Parisa and Akbarzadeh, Marzieh (2020) The effects of cashew nut intake on lipid profile and blood pressure: a systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 50. a102387. ISSN 0965-2299

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Abstract

Background: Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD). Some studies have suggested that the consumption of nuts may reduce CVD risk.
Objective: The present systematic review and meta-analysis was conducted to investigate the efficacy of cashew nut consumption on lipid profile and blood pressure.
Methods: PubMed, Embase, Scopus, Web of Science and Cochrane Library were systematically searched to identify randomized control trials (RCTs) examining the effects of cashew nut intake on serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or diastolic blood pressure (DBP) until 15 November 2019. Random-effects or fixed-effects models were used to pool weighted mean difference (WMD) and 95% confidence intervals (CI). Potential publication bias was assessed using Egger’s test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results.
Results: A meta-analysis on 392 participants showed that cashew consumption had no significant effects on lipid profile and DBP. However, there was a significant reduction in SBP (WMD = -3.39, 95% CI = [-6.13, -0.65], P = 0.01, I2 = 0.0%) in the group receiving an increased cashew nut intake compared to the controls. There was no significant publication bias in the meta-analysis. A sensitivity analysis, omitting single trials in turn, did not have a significant effect on the pooled results.
Conclusion: This meta-analysis demonstrated that cashew nut consumption might reduce SBP but has no effects on lipid profile and DBP.

Item Type: Article
Keywords: Cashew nut, Lipid profile, Blood pressure, Review, Meta-analysis
Schools and Departments: Brighton and Sussex Medical School > Division of Medical Education
Depositing User: Cherie Elody
Date Deposited: 12 May 2020 08:17
Last Modified: 12 May 2020 08:30
URI: http://sro.sussex.ac.uk/id/eprint/91205

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