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Perigenual anterior cingulate morphology covaries with perceived social standing
journal contribution
posted on 2023-06-09, 21:08 authored by Peter J Gianaros, Jeffrey A Horenstein, Sheldon Cohen, Karen A Matthews, Sarah M Brown, Janine D Flory, Hugo CritchleyHugo Critchley, Stephen B Manuck, Ahmad R HaririLow socioeconomic status (SES) increases the risk for developing psychiatric and chronic medical disorders. A stress-related pathway by which low SES may affect mental and physical health is through the perception of holding a low social standing, termed low subjective social status. This proposal implicates overlapping brain regions mediating stress reactivity and socioemotional behaviors as neuroanatomical substrates that could plausibly link subjective social status to health-related outcomes. In a test of this proposal, we used a computational structural neuroimaging method (voxel-based morphometry) in a healthy community sample to examine the relationships between reports of subjective social status and regional gray matter volume. Results showed that after accounting for potential demographic confounds, subclinical depressive symptoms, dispositional forms of negative emotionality and conventional indicators of SES, self-reports of low subjective social status uniquely covaried with reduced gray matter volume in the perigenual area of the anterior cingulate cortex (pACC)-a brain region involved in experiencing emotions and regulating behavioral and physiological reactivity to psychosocial stress. The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health. © 2007 The Author(s).
History
Publication status
- Published
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- Published version
Journal
Social Cognitive and Affective NeuroscienceISSN
1749-5016Publisher
Oxford University PressExternal DOI
Issue
3Volume
2Page range
161-173Event location
EnglandDepartment affiliated with
- BSMS Neuroscience Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2020-04-22First Open Access (FOA) Date
2020-04-22First Compliant Deposit (FCD) Date
2020-04-22Usage metrics
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