Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis di.pdf (875.44 kB)
Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis diagnosed in primary care: a pilot randomised controlled trial
journal contribution
posted on 2023-06-09, 20:58 authored by Claudia S Estcourt, Lorna J Sutcliffe, Andrew Copas, Catherine H Mercer, Tracy E Roberts, Louise J Jackson, Merle Symonds, Laura Tickle, Pamela Muniina, Greta Rait, Anne M Johnson, Kazeem Aderogba, Sarah Creighton, Jackie CassellBackground Accelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two APT models in community settings. Methods Three-arm pilot RCT of two adjunct APT interventions: APTHotline (telephone assessment of partner(s) plus standard PN) and APTPharmacy (community pharmacist assessment of partner(s) plus routine PN), versus standard PN alone (patient referral). Index patients were women diagnosed with genital chlamydia in 12 general practices and three community contraception and sexual health (CASH) services in London and south coast of England, randomised between 1 September 2011 and 31 July 2013. Results 199 women described 339 male partners, of whom 313 were reported by the index as contactable. The proportions of contactable partners considered treated within 6 weeks of index diagnosis were APTHotline 39/111 (35%), APTPharmacy 46/100 (46%), standard patient referral 46/102 (45%). Among treated partners, 8/39 (21%) in APTHotline arm were treated via hotline and 14/46 (30%) in APTPharmacy arm were treated via pharmacy. Conclusions The two novel primary care APT models were acceptable, feasible, compliant with regulations and capable of achieving acceptable outcomes within a pilot RCT but intervention uptake was low. Although addition of these interventions to standard PN did not result in a difference between arms, overall PN uptake was higher than previously reported in similar settings, probably as a result of introducing a formal evaluation. Recruitment to an individually randomised trial proved challenging and full evaluation will likely require service-level randomisation.
History
Publication status
- Published
File Version
- Published version
Journal
Sexually Transmitted InfectionsISSN
1368-4973Publisher
BMJ Publishing GroupExternal DOI
Issue
8Volume
91Page range
548-554Event location
EnglandDepartment affiliated with
- Primary Care and Public Health Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2020-03-26First Open Access (FOA) Date
2020-03-26First Compliant Deposit (FCD) Date
2020-03-26Usage metrics
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No categories selectedKeywords
Chlamydia TrachomatisClinical Sti CareCompex InterventionsPartner NotificationPrimary CareAdultAmbulatory CareChlamydia InfectionsContact TracingFeasibility StudiesHumansMalePatient Acceptance Of Health CarePilot ProjectsPrimary Health CareProgram DevelopmentReferral And ConsultationSexual BehaviorSexual Partners
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