Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases subgroup analyses of the RESTART randomised, op.pdf (766.6 kB)
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
journal contribution
posted on 2023-06-09, 20:40 authored by Rustam Al-Shahi Salman, David P Minks, Dipayan Mitra, Mark A Rodrigues, Priya Bhatnagar, Johann C du Plessis, Yogish Joshi, Martin S Dennis, Gordon D Murray, David E Newby, Peter A G Sandercock, Nikola Sprigg, Jacqueline Stephen, Cathie L M Sudlow, David J Werring, William N Whiteley, Joanna M Wardlaw, Philip M WhiteBackground Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy.
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Publication status
- Published
File Version
- Published version
Journal
Lancet NeurologyISSN
1474-4422Publisher
ElsevierExternal DOI
Issue
7Volume
18Page range
643-652Department affiliated with
- BSMS Publications
Full text available
- Yes
Peer reviewed?
- Yes
Contributors
C RajkumarLegacy Posted Date
2020-03-19First Open Access (FOA) Date
2020-03-19First Compliant Deposit (FCD) Date
2020-02-20Usage metrics
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