Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

Al-Shahi Salman, Rustam, Dennis, M S, Sandercock, P A G, Sudlow, C L M, Wardlaw, J M, Whiteley, W N, Murray, G D, Stephen, J, Newby, D E, Sprigg, N, Werring, D J, White, P M, Baigent, Colin, Lasserson, Daniel, Rajkumar, Chakravarthi, RESTART Collaboration, and others, (2019) Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet, 393 (10191). 2613 -2623. ISSN 0140-6736

[img] PDF - Published Version
Available under License Creative Commons Attribution-NonCommercial No Derivatives.

Download (545kB)

Abstract

Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Depositing User: Angela Blazey
Date Deposited: 16 Mar 2020 08:35
Last Modified: 16 Mar 2020 08:45
URI: http://sro.sussex.ac.uk/id/eprint/89679

View download statistics for this item

📧 Request an update