Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART) a randomised, open-label trial.pdf (533.18 kB)
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
journal contribution
posted on 2023-06-09, 20:28 authored by Rustam Al-Shahi Salman, M S Dennis, P A G Sandercock, C L M Sudlow, J M Wardlaw, W N Whiteley, G D Murray, J Stephen, D E Newby, N Sprigg, D J Werring, P M White, Colin Baigent, Daniel Lasserson, Chakravarthi Rajkumar, RESTART Collaboration, othersAntiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
History
Publication status
- Published
File Version
- Published version
Journal
LancetISSN
0140-6736Publisher
ElsevierExternal DOI
Issue
10191Volume
393Page range
2613 -2623Department affiliated with
- Clinical and Experimental Medicine Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2020-03-16First Open Access (FOA) Date
2020-03-16First Compliant Deposit (FCD) Date
2020-03-13Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC