The impact of diagnostic microbiology on de-escalation of antimicrobial therapy in hospitalised adults

Hamilton, William L, Pires, Sacha-Marie, Lippett, Samantha, Gudka, Vikesh, Cross, Elizabeth L A and Llewelyn, Martin J (2020) The impact of diagnostic microbiology on de-escalation of antimicrobial therapy in hospitalised adults. BMC Infectious Diseases, 20. a102. ISSN 1471-2334

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Abstract

Minimising antimicrobial overuse is needed to limit antimicrobial resistance. There is little evidence on how often microbiological testing informs antimicrobial de-escalation (e.g. stopping, shortening duration, switching to narrower spectrum or intravenous to oral switch) at 48-72 hour “review and revise”. We performed a patient level analysis of diagnostic microbiology and antimicrobial prescribing to determine the impact of microbiology results on antimicrobial review outcomes.

Item Type: Article
Keywords: Antimicrobial resistance; diagnostic microbiology; antibiotics; prescribing; antimicrobial stewardship
Schools and Departments: Brighton and Sussex Medical School > Global Health and Infection
Research Centres and Groups: Brighton and Sussex Centre for Global Health Research
Depositing User: Manuela Mcdermid
Date Deposited: 29 Jan 2020 09:22
Last Modified: 05 Feb 2020 10:30
URI: http://sro.sussex.ac.uk/id/eprint/89646

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