University of Sussex
Browse
Menlove et al_pre-print copy.pdf (941.7 kB)

Predictors of anxiety after stroke: a systematic review of observational studies

Download (941.7 kB)
journal contribution
posted on 2023-06-09, 20:11 authored by Leanne Menlove, Elise Crayton, Ian Kneebone, Rhani Allen-Crooks, Elisabeth Otto, Helena HarderHelena Harder
Background: Anxiety disorders or symptoms are relatively common following stroke. A better understanding of the predictors of anxiety in stroke patients may improve the management of these disorders. The current review was conducted to determine the predictors of anxiety following stroke. Methods: Relevant articles concerning population, hospital or rehabilitation-based studies were identified by searching 10 electronic databases up to May 2014. Methodological quality appraisal, including the validity of prognostic models and data extraction were conducted by three reviewers. Results: A total of 18 studies were identified. Data from three population-based studies including 8130 patients, 8 hospital-based studies including 1199 patients, and 7 rehabilitation-based studies including 1103 patients was evaluated. Pre-stroke depression, stroke severity, early anxiety and dementia or cognitive impairment following stroke were the main predictors of post stroke anxiety. Older age, physical disability or impairment, and use of antidepressant drugs were not associated with presence of anxiety. Limitations of studies included wide variation in screening tools and cut-off scores, variability in the time frame of screening for anxiety, use of extensive exclusion criteria and questionable statistical internal and external validity of the models. Conclusions: Lack of methodological and statistical rigour affects the validity of proposed models to predict anxiety after stroke. Future research should focus on testing proposed models on both internal and external samples to ultimately inform future clinical practice.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Journal of Stroke and Cerebrovascular Diseases

ISSN

1052-3057

Publisher

Elsevier

Issue

6

Volume

24

Page range

1107-1117

Department affiliated with

  • Sussex Health Outcomes Research & Education in Cancer (SHORE-C) Publications

Research groups affiliated with

  • Sussex Health Outcomes Research and Education in Cancer Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Contributors

Helena Harder

Legacy Posted Date

2020-01-10

First Open Access (FOA) Date

2020-01-10

First Compliant Deposit (FCD) Date

2020-01-09

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC