GREENWOOD_Asian Journal of Psychiatry_MAY_2019_author_copy.pdf (271.73 kB)
Tobacco smoking and nicotine dependence in first episode and established psychosis
journal contribution
posted on 2023-06-09, 19:07 authored by John Lally, Gilda Spaducci, Poonam Gardner-Sood, Zerrin Atakan, Kathryn GreenwoodKathryn Greenwood, Marta Di Forti, Khalida Ismail, Kieran C. Murphy, Shubulade Smith, Ann McNeill, Robin M. Murray, Fiona GaughranAim People with psychotic disorders have increased premature mortality in comparison with the general population, with high rates of cigarette use a contributing factor. We aimed to describe the prevalence of cigarette use and nicotine dependence (ND) in first episode psychosis (FEP), and established psychosis; and to investigate associations between clinical symptoms and ND. Methodology Smoking and clinical data were collected from two cohorts: 181 people with FEP recruited as part of the Physical Health and Substance Use Measures in First Onset Psychosis (PUMP) study and from 432 people with established psychosis recruited as part of the Improving physical health and reducing substance use in psychosis randomised controlled trial (IMPaCT RCT). Results The prevalence of cigarette smoking was 78% in FEP and 62% in established psychosis. Forty nine percent (n=60) of smokers in the FEP cohort and 69% (n=183) of smokers with established psychosis were highly nicotine dependent. Being a highly nicotine dependent smoker was significantly associated with higher PANSS positive symptom scores (F= 5.480 p= 0.004), and with decreased scores on the Rosenberg self-esteem scale (F=3.261, p=0.039) in established psychosis. There was no diagnostic specificity identified in relation to smoking or ND in both groups. Conclusion High rates of cigarette usage and nicotine dependence are problems from the early stages of psychosis. ND is higher in people with established psychosis. Smoking cessation strategies as part of comprehensive management of psychotic disorders at every stage require further development and evaluation.
History
Publication status
- Published
File Version
- Accepted version
Journal
Asian Journal of PsychiatryISSN
18762018Publisher
ElsevierExternal DOI
Volume
43Page range
125-131Department affiliated with
- Psychology Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2019-09-27First Open Access (FOA) Date
2020-05-04First Compliant Deposit (FCD) Date
2019-09-20Usage metrics
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