Compounds that modulates AMPA receptor function

The University of Sussex, Cardiff University, University College Cardiff Consultants Limited; Ward, Simon; Beswick, Paul; Pennicott, Lewis; Reuillon, Tristan; Chuckowree, Irina; Villalonga-Barber, Carolina; Porter, Roderick (2019) Compounds that modulates AMPA receptor function. PCT/GB2019/050578.

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Abstract

The invention provides compounds of the formula (I): (I) wherein A1, A2, R2, R4, B1, B2, X, X1, n, a and b are as defined are defined in the specification, to pharmaceutical compositions comprising the compounds and the compounds for use as medicaments. The compounds potentiate AMPA receptor function and are expected to be useful in the treatment of central nervous system disorders, for example in the treatment of depressive disorders, mood disorders and cognitive dysfunction associated with neuropsychiatric disorders such as schizophrenia.

Item Type: Patent
Schools and Departments: School of Life Sciences > Chemistry
Research Centres and Groups: Sussex Drug Discovery Centre
Subjects: R Medicine
Depositing User: Lewis Pennicott
Date Deposited: 30 Sep 2019 09:03
Last Modified: 30 Sep 2019 09:04
URI: http://sro.sussex.ac.uk/id/eprint/86323

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