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Design and statistical analysis of irregular porous scaffolds for orthopedic reconstruction based on Voronoi tessellation and fabricated via selective laser melting (SLM)
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posted on 2023-06-09, 18:40 authored by Yue Du, Huixin Liang, Deqiao Xie, Ning Mao, Jianfeng Zhao, Zongjun Tian, Chang WangChang Wang, Lida ShenThe use of irregular porous structures in bone tissue engineering (BTE) has attracted increasing attention. An irregular porous structure is similar to that of human bone tissue and is more suitable for bone tissue growth than a regular porous structure. In this study, we propose a top-down design method for constructing irregular porous structures based on Voronoi tessellation. The model constructed with this method was fabricated by selective laser melting (SLM) and industrial computed tomography (CT) was used to measure the morphological characteristics; the mechanical properties were obtained by quasi-static compressive test. The experimental results showed that the samples had a porosity ranging from 50% to 85%, an average pore diameter ranging from 512 to 998 um, an apparent elastic modulus ranging from 2.13 to 3.97 GPa, and a compressive strength ranging from 78.99 to 130.5 Mpa and met the artificial implant requirements. Three regression equations were established between the three design parameters and the porosity, apparent elastic modulus, and compressive strength using a response surface methodology (RSM). The equations allow for better control of the irregular porous structure and the prediction of the properties.
History
Publication status
- Published
Journal
Materials Chemistry and PhysicsISSN
0254-0584Publisher
ElsevierVolume
239Page range
121968Department affiliated with
- Engineering and Design Publications
Research groups affiliated with
- Dynamics, Control and Vehicle Research Group Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2019-08-19First Compliant Deposit (FCD) Date
2019-08-16Usage metrics
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