Design and statistical analysis of irregular porous scaffolds for orthopedic reconstruction based on Voronoi tessellation and fabricated via selective laser melting (SLM)

Du, Yue, Liang, Huixin, Xie, Deqiao, Mao, Ning, Zhao, Jianfeng, Tian, Zongjun, Wang, Changjiang and Shen, Lida (2020) Design and statistical analysis of irregular porous scaffolds for orthopedic reconstruction based on Voronoi tessellation and fabricated via selective laser melting (SLM). Materials Chemistry and Physics, 239. p. 121968. ISSN 0254-0584

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Abstract

The use of irregular porous structures in bone tissue engineering (BTE) has attracted increasing attention. An irregular porous structure is similar to that of human bone tissue and is more suitable for bone tissue growth than a regular porous structure.

In this study, we propose a top-down design method for constructing irregular porous structures based on Voronoi tessellation. The model constructed with this method was fabricated by selective laser melting (SLM) and industrial computed tomography (CT) was used to measure the morphological characteristics; the mechanical properties were obtained by quasi-static compressive test. The experimental results showed that the samples had a porosity ranging from 50% to 85%, an average pore diameter ranging from 512 to 998 um, an apparent elastic modulus ranging from 2.13 to 3.97 GPa, and a compressive strength ranging from 78.99 to 130.5 Mpa and met the artificial implant requirements. Three regression equations were established between the three design parameters and the porosity, apparent elastic modulus, and compressive strength using a response surface methodology (RSM). The equations allow for better control of the irregular porous structure and the prediction of the properties.

Item Type: Article
Schools and Departments: School of Engineering and Informatics > Engineering and Design
Research Centres and Groups: Dynamics, Control and Vehicle Research Group
Subjects: T Technology > TA Engineering (General). Civil engineering (General) > TA0174 Engineering design
Depositing User: Chang Wang
Date Deposited: 19 Aug 2019 10:57
Last Modified: 19 Aug 2019 11:00
URI: http://sro.sussex.ac.uk/id/eprint/85531

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