Rass, Ulrich (2019) Freedom of movement. Nature Chemical Biology, 15 (37). pp. 209-210. ISSN 1552-4450

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Abstract

Holliday junction resolvases lock dynamic DNA four-way junctions into specific structural conformations for symmetric DNA cleavage. Single-molecule studies now reveal that resolvases can relax their grip, enabling Holliday junction conformer transitions and branch migration in the enzyme-bound form.

Item Type:	Article
Keywords:	Holliday junction resovases, homologous recombination
Schools and Departments:	School of Life Sciences > Sussex Centre for Genome Damage and Stability
Research Centres and Groups:	Genome Damage and Stability Centre
Subjects:	Q Science > Q Science (General)
Depositing User:	Ulrich Rass
Date Deposited:	22 Jan 2019 10:24
Last Modified:	21 Jul 2019 01:00
URI:	http://sro.sussex.ac.uk/id/eprint/81416

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