Freedom of movement

Rass, Ulrich (2019) Freedom of movement. Nature Chemical Biology, 15 (37). pp. 209-210. ISSN 1552-4450

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Holliday junction resolvases lock dynamic DNA four-way junctions into specific structural conformations for symmetric DNA cleavage. Single-molecule studies now reveal that resolvases can relax their grip, enabling Holliday junction conformer transitions and branch migration in the enzyme-bound form.

Item Type: Article
Keywords: Holliday junction resovases, homologous recombination
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Research Centres and Groups: Genome Damage and Stability Centre
Subjects: Q Science > Q Science (General)
Depositing User: Ulrich Rass
Date Deposited: 22 Jan 2019 10:24
Last Modified: 21 Jul 2019 01:00

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