The relationship between health-related quality-of-life and disability in patients with controlled epilepsy

Quintas, Rui, Alvarez, Ana Sabela, Koutsogeorgou, Eleni, Cerniauskaite, Milda, Meucci, Paolo, Sattin, Davide, Leonardi, Matilde and Raggi, Alberto (2012) The relationship between health-related quality-of-life and disability in patients with controlled epilepsy. American Journal of Physical Medicine and Rehabilitation, 91 (13). S31-S38. ISSN 0894-9115

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The aims this study were to assess the impact of epilepsy on the health-related quality-of-life (HRQoL) of patients and on patterns of disability and to describe the relationship between disability and HRQoL in adult patients with controlled epilepsy.

Disability was measured with the World Health Organization Disability Assessment Schedule, second version (WHO-DAS II), whereas HRQoL was measured with the 36-item Short-Form Health Survey (SF-36). The relationships between SF-36 and WHO-DAS II were evaluated with Pearson correlation. The impact of epilepsy on disability and HRQoL was assessed by comparing WHO-DAS II and SF-36 scores with the Italian normative values and by evaluating different disability and HRQoL profiles in patients self-reporting change in health state against those reporting no change.

Few differences between patients' and normative scores were observed. In particular, patients with a stable health state reported higher HRQoL and lower disability status, compared with those reporting an improvement or a decline in health state. The relationships between WHO-DAS II and SF-36 were significant but were generally low or moderate.

Disability and HRQoL scores of patients with controlled epilepsy were not significantly different compared with those of the general population, in particular among stable patients. Measures of HRQoL and disability evaluate different psychosocial aspects of epilepsy and can be used jointly to evaluate outcomes.

Item Type: Article
Schools and Departments: School of Law, Politics and Sociology > Sociology
Subjects: H Social Sciences > H Social Sciences (General)
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry > RC0346 Neurology. Diseases of the nervous system Including speech disorders > RC0349.8 Therapeutics > RC0360 Diseases of the central nervous system > RC0372 Epilepsy
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Depositing User: Eleni Koutsogeorgou
Date Deposited: 13 Nov 2018 15:40
Last Modified: 13 Nov 2018 15:47
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