Exploring the socioethical dilemmas in the use of a global health archive

Holmes, Matthew James Vaughton, Morris, Isla-Kate, Williams, Anthony, Le Blond, Jennifer, Cranna, Victoria and Davey, Gail (2019) Exploring the socioethical dilemmas in the use of a global health archive. Research Ethics, 15 (1). pp. 1-9. ISSN 1747-0161

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Abstract

A global health archive consisting of podoconiosis tissue slides and blocks (which was collected and imported into the UK before the introduction of the Human Tissue Act), was donated to Brighton & Sussex Medical School in 2014. There is little guidance on the socioethical and legal issues surrounding the retrospective use of archived or ‘abandoned’ tissue samples, which poses a number of questions relating to the ethical standing of the archive.

There is a great deal of interpretation in the guidelines that are currently in existence, however modern ethical principles cannot be applied as it is not feasible to either reconsent or retrospectively seek approval. Our research team believed that it was unethical to leave the archive in storage, as this option favours neither researcher nor subjects. Permission was obtained from the Human Tissue Authority and a local ethics board for the tissues to be utilised in on-going research on podoconiosis aetiology.

There is a delicate balance between the benefits gained by society relating to the development and progress of scientific research and the risks to the donor regarding the reuse of their tissues. Clearer guidelines should be made available to ensure that researchers are able to re-use tissue archives in contemporary research.

Item Type: Article
Keywords: Ethics, Bioethics, Tissue bank, archive, podoconiosis, global health,biobank
Schools and Departments: Brighton and Sussex Medical School > Global Health and Infection
Subjects: R Medicine > R Medicine (General) > R723 Medical philosophy. Medical ethics
Depositing User: Deborah Miller
Date Deposited: 25 Oct 2018 14:13
Last Modified: 11 Jul 2019 16:00
URI: http://sro.sussex.ac.uk/id/eprint/79686

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