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Marais, Gabriel, Nouvellet, Pierre, Keightley, Peter D and Charlesworth, Brian (2005) Intron size and exon evolution in Drosophila. Genetics, 170 (1). pp. 481-485. ISSN 0016-6731
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Official URL: http://dx.doi.org/10.1534/genetics.104.037333
Abstract
We have found a negative correlation between evolutionary rate at the protein level (as measured by d(N)) and intron size in Drosophila. Although such a relation is expected if introns reduce Hill-Robertson interference within genes, it seems more likely to be explained by the higher abundance of cis-regulatory elements in introns (especially first introns) in genes under strong selective constraints.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Evolution, Behaviour and Environment |
Depositing User: | Pierre Nouvellet |
Date Deposited: | 17 Aug 2018 15:34 |
Last Modified: | 02 Jul 2019 14:49 |
URI: | http://sro.sussex.ac.uk/id/eprint/77923 |
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