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Membrane excitability in cleavage-arrested, differentiated cells
A rare glimpse of patterns of cell determination in the early embryo is provided by a recent article in the Journal of Physiology, in which T. Hirano and colleagues2 report that in. cleavage-arrested ascidian embryos, left the equivalent time to hatching, identified blastomeres differentiate to produce daughter cells with one of four well-defined types of membrane excitability; neural, epidermal, muscular or non-excitable. This interesting system contributes to our understanding of mosaicism and regulation in early development, and may enable detailed study of the development of membrane excitability.
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Publication status
- Published
Journal
Trends in NeurosciencesISSN
0166-2236Publisher
ElsevierExternal DOI
Issue
6Volume
7Page range
182-183Department affiliated with
- Neuroscience Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2017-07-26Usage metrics
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