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Gap junctional communication and development
Embryonic development requires extensive interaction between cells; cell-to-cell communication through gap junctions may be one mechanism involved. Much correlative evidence suggests gap junctions are involved in cellular interactions during development. Recently, the biological role of junctions has been investigated using antibodies prepared against the major rat liver gap junction protein. Disrupting normal patterns of intercellular communication with such antibodies can drastically perturb development. Recent experiments emphasize, in particular, the importance of gap junctional communication for patterning processes.
History
Publication status
- Published
Journal
Trends in NeurosciencesISSN
0166-2236Publisher
ElsevierExternal DOI
Issue
1Volume
12Page range
12-16Department affiliated with
- Neuroscience Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2017-07-26Usage metrics
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