Gap junctional communication and development

Guthrie, S and Gilula, N (1989) Gap junctional communication and development. Trends in Neurosciences, 12 (1). pp. 12-16. ISSN 0166-2236

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Embryonic development requires extensive interaction between cells; cell-to-cell communication through gap junctions may be one mechanism involved. Much correlative evidence suggests gap junctions are involved in cellular interactions during development. Recently, the biological role of junctions has been investigated using antibodies prepared against the major rat liver gap junction protein. Disrupting normal patterns of intercellular communication with such antibodies can drastically perturb development. Recent experiments emphasize, in particular, the importance of gap junctional communication for patterning processes.

Item Type: Article
Schools and Departments: School of Life Sciences > Neuroscience
Depositing User: Stephanie McGuire
Date Deposited: 26 Jul 2017 12:54
Last Modified: 26 Jul 2017 12:54
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