Romero_et_al-2017-Chemistry_-_A_European_Journal.pdf (1.45 MB)
Base-mediated generation of ketenimines from ynamides: direct access to azetidinimines by an imino staudinger synthesis
journal contribution
posted on 2023-06-09, 07:00 authored by Eugénie Romero, Corinne Minard, Mohamed Benchekroun, Sandrine Ventre, Pascal Retailleau, Robert H Dodd, Kevin CariouYnamides were used as precursors for the in situ generation of highly reactive ketenimines which could be trapped with imines in a [2+2] cycloaddition. This imino Staudinger synthesis led to a variety of imino-analogs of ß-lactams, namely azetidinimines (20 examples), that could be further functionalized through a broad range of transformations.
History
Publication status
- Published
File Version
- Accepted version
Journal
Chemistry - A European JournalISSN
0947-6539Publisher
WileyExternal DOI
Issue
53Volume
23Page range
12991-12994Department affiliated with
- Chemistry Publications
Research groups affiliated with
- Sussex Drug Discovery Centre Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2017-07-28First Open Access (FOA) Date
2018-08-03First Compliant Deposit (FCD) Date
2017-07-28Usage metrics
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