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Patterning the hindbrain

journal contribution
posted on 2023-06-09, 06:13 authored by Sarah GuthrieSarah Guthrie
Of paramount importance for hindbrain patterning is positional information that is laid down along the rostrocaudal axis. Recent findings suggest that retinoic acid may establish rostrocaudal domains of gene expression that confer on rhombomeres their specific identities; these domains display different responses to dorsoventral signals that further refine the repertoire of cellular fates therein. After rhombomere boundaries form, a high degree of segmental autonomy is balanced by a continuing capacity for interaction along the rostrocaudal axis, exemplified by the generation of the neural crest.

History

Publication status

  • Published

Journal

Current Opinion in Neurobiology

ISSN

0959-4388

Publisher

Elsevier

Issue

1

Volume

6

Page range

41-48

Department affiliated with

  • Neuroscience Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2017-05-09

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