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Patterning the hindbrain
Of paramount importance for hindbrain patterning is positional information that is laid down along the rostrocaudal axis. Recent findings suggest that retinoic acid may establish rostrocaudal domains of gene expression that confer on rhombomeres their specific identities; these domains display different responses to dorsoventral signals that further refine the repertoire of cellular fates therein. After rhombomere boundaries form, a high degree of segmental autonomy is balanced by a continuing capacity for interaction along the rostrocaudal axis, exemplified by the generation of the neural crest.
History
Publication status
- Published
Journal
Current Opinion in NeurobiologyISSN
0959-4388Publisher
ElsevierExternal DOI
Issue
1Volume
6Page range
41-48Department affiliated with
- Neuroscience Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2017-05-09Usage metrics
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