Patterning the hindbrain

Guthrie, Sarah (1996) Patterning the hindbrain. Current Opinion in Neurobiology, 6 (1). pp. 41-48. ISSN 0959-4388

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Of paramount importance for hindbrain patterning is positional information that is laid down along the rostrocaudal axis. Recent findings suggest that retinoic acid may establish rostrocaudal domains of gene expression that confer on rhombomeres their specific identities; these domains display different responses to dorsoventral signals that further refine the repertoire of cellular fates therein. After rhombomere boundaries form, a high degree of segmental autonomy is balanced by a continuing capacity for interaction along the rostrocaudal axis, exemplified by the generation of the neural crest.

Item Type: Article
Schools and Departments: School of Life Sciences > Neuroscience
Depositing User: Ashleigh Cave
Date Deposited: 09 May 2017 14:11
Last Modified: 11 Nov 2019 11:48
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