Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort

Thompson, A, Marwaha, S, Winsper, C, Everard, L, Jones, P B, Fowler, D, Amos, T, Freemantle, N, Singh, S P, Marshall, M, Sharma, V and Birchwood, M (2016) Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort. Acta Psychiatrica Scandinavica, 134 (4). pp. 321-328. ISSN 0001-690X

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The incidence and outcome of first-episode substance-induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1-year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first-episode cohort.

Data were from a large (n = 1027) cohort of first-episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months.

There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group.

First-episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients.

Item Type: Article
Keywords: First episode psychosis, Substance induced psychotic disorders, Outcome, Cohort study
Schools and Departments: School of Psychology > Psychology
Subjects: B Philosophy. Psychology. Religion
Depositing User: Alexandra Barnard
Date Deposited: 12 Aug 2016 07:04
Last Modified: 02 Jul 2019 18:49

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