Kumar, Prashant, Irrgang, Torsten, Kostakis, George E and Kempe, Rhett (2016) Phosphine-free chiral iridium catalysts for asymmetric catalytic hydrogenation of simple ketones. RSC Advances, 6 (45). pp. 39335-39342. ISSN 2046-2069
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Abstract
Novel pyridylalkylamine and aminopyridinato ligand stabilized iridium complexes with no P ligand are introduced. These complexes have been investigated as catalysts for asymmetric hydrogenation of simple ketones, resulting in an active catalyst for bulky alkyl aryl ketones that is α-methylpropiophenone. The ligands were synthesized from inexpensive starting materials and their modular design allows for the introduction of a broad variety of substitution patterns. Additionally, better activity and selectivity was observed at 20 °C and 20 bar H2 pressure with a catalyst loading as low as 0.05 mol% iridium. These phosphorus free catalysts have always been a central issue in both academic and industrial research.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Chemistry |
Subjects: | Q Science > QD Chemistry > QD0146 Inorganic chemistry |
Depositing User: | Georgios Kostakis |
Date Deposited: | 15 Jun 2016 10:40 |
Last Modified: | 02 Jul 2019 18:21 |
URI: | http://sro.sussex.ac.uk/id/eprint/61503 |
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