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Burst firing enhances neural ouput correlation

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posted on 2023-06-09, 01:10 authored by Ho Ka Chan, Dong-Ping Yang, Changsong Zhou, Thomas NowotnyThomas Nowotny
Neurons communicate and transmit information predominantly through spikes. Given that experimentally observed neural spike trains in a variety of brain areas can be highly correlated, it is important to investigate how neurons process correlated inputs. Most previous work in this area studied the problem of correlation transfer analytically by making significant simplifications on neural dynamics. Temporal correlation between inputs that arises from synaptic filtering, for instance, is often ignored when assuming that an input spike can at most generate one output spike. Through numerical simulations of a pair of leaky integrate-and-fire (LIF) neurons receiving correlated inputs, we demonstrate that neurons in the presence of synaptic filtering by slow synapses exhibit strong output correlations. We then show that burst firing plays a central role in enhancing output correlations, which can explain the above-mentioned observation because synaptic filtering induces bursting. The observed changes of correlations are mostly on a long time scale. Our results suggest that other features affecting the prevalence of neural burst firing in biological neurons, e.g., adaptive spiking mechanisms, may play an important role in modulating the overall level of correlations in neural networks.

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Publication status

  • Published

File Version

  • Published version

Journal

Frontiers in Computational Neuroscience

ISSN

1662-5188

Publisher

Frontiers Media

Volume

10

Article number

a42

Department affiliated with

  • Informatics Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2016-05-09

First Open Access (FOA) Date

2016-05-09

First Compliant Deposit (FCD) Date

2016-05-09

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