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Mesoporous silica nanoparticles in nanotechnology

journal contribution
posted on 2023-06-09, 00:11 authored by Dennis Douroumis, Ichioma Onyesom, Mohammed Maniruzzaman, John Mitchell
Mesoporous silica nanoparticles (MSNs) are a versatile drug delivery system that can be used for loading of different guest molecules such as peptides, proteins, anticancer agents, and genetic material. MSNs are considered promising drug carriers due to their tuneable particle size, pore structure, and surface functionalization. Thus, MSNs provide opportunities for their effective application in a wide variety of fields. In the current review, we discuss both conventional and advanced MSNs synthesis methods, including their applications for drug delivery, gatekeepers, and biosensors. In addition, the research progress in biocompatibility, cytotoxicity, and internalization mechanisms is reported.

History

Publication status

  • Published

Journal

Critical Reviews in Biotechnology

ISSN

0738-8551

Publisher

Taylor & Francis

Issue

3

Volume

33

Page range

229-245

Department affiliated with

  • Chemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2016-01-29

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