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A novel non-invasive sensor based on electric field detection for cardio-electrophysiology in zebrafish embryos

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posted on 2023-06-09, 00:09 authored by Elizabeth Rendon-MoralesElizabeth Rendon-Morales, Helen Prance, Robert Prance, Rodrigo Aviles-Espinosa
Currently, there is no effective sensing technology available to monitor the electrocardiogram activity of the living zebrafish heart during early developmental stages. Most of the methods are based either on the use of simple visual inspections which are limited to quantifying the heart rate or invasive methodologies which require the insertion of electrodes or heart explantation techniques both requiring the use of expensive differential amplifiers and noise isolated environments. In this paper we report the continuous detection of the cardiac electrical activity in embryonic zebrafish using a non-invasive approach. We present a portable and cost-effective platform based on the Electric Potential Sensing technology, to monitor in vivo electrocardiogram activity from the zebrafish heart. This proof of principle demonstration shows how electrocardiogram measurements from embryonic zebrafish may become accessible by using the electric field detection method. We present results obtained using the experimental prototype, which enables the acquisition of cardio-electrophysiological signals from in vivo zebrafish embryos.

History

Publication status

  • Published

Event name

Biosensors Congres Elsevier 2016

Event location

Gothenburg, Sweden

Event type

conference

Event date

25-27 May 2016

Department affiliated with

  • Informatics Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2016-02-22

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