Garfinkel, Sarah N, Eccles, Jessica A and Critchley, Hugo D (2015) The heart, the brain, and the regulation of emotion. JAMA Psychiatry, 72 (11). pp. 1071-1072. ISSN 2168-622X

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Abstract

Müller and colleagues1 present a study showing that an electroencephalographic signature of the brain’s representation of internal bodily responses (the amplitude of heartbeat evoked potential) is abnormally attenuated in patients with borderline personality disorder (BPD). This deficit predicts symptoms, including the degree of emotional instability, and correlates with structural differences in the gray matter volume in the insula and the anterior cingulate cortex, brain regions engaged during emotional regulation and implicated in the integrative control of mind and body. Patients with BPD in remission show a more normative heartbeat evoked potential, suggesting that strategies to improve mental and physiological integration may enhance psychotherapeutic interventions for this patient group.

Item Type:	Article
Schools and Departments:	Brighton and Sussex Medical School > Neuroscience
Subjects:	R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
Depositing User:	Jonathan Williams
Date Deposited:	14 Dec 2015 12:27
Last Modified:	25 Jul 2017 13:39
URI:	http://sro.sussex.ac.uk/id/eprint/58818

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