Synaptic vesicle pools: principles, properties and limitations

Fowler, Milena Wagner and Staras, Kevin (2015) Synaptic vesicle pools: principles, properties and limitations. Experimental Cell Research, 335 (2). pp. 150-156. ISSN 0014-4827

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It is around three decades since the term ‘pool’ was first used to refer to a sub-population of presynaptic vesicles differentiated on the basis of their specific functional or structural characteristics. Subsequently, the idea that vesicle clusters can be sub-categorized has been widely embraced, offering an important framework for elucidating elemental principles of synaptic operation and uncovering presynaptic substrates of modulation. This short review aims to provide a contemporary perspective on the vesicle pool field, identify key remaining questions, and also to consider some of the limitations of the pool concept.

Item Type: Article
Schools and Departments: School of Life Sciences > Neuroscience
Depositing User: Kevin Staras
Date Deposited: 25 Nov 2015 15:22
Last Modified: 25 Nov 2015 15:44
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