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Non-invasive electrocardiogram detection of in vivo zebrafish embryos using electric potential sensors
journal contribution
posted on 2023-06-08, 22:54 authored by Elizabeth Rendon-MoralesElizabeth Rendon-Morales, Robert Prance, Helen Prance, Rodrigo Aviles-EspinosaIn this Letter we report the continuous detection of the cardiac electrical activity in embryonic zebrafish using a non-invasive approach. We present a portable and cost-effective platform based on the Electric Potential Sensing technology, to monitor in vivo electrocardiogram activity from the zebrafish heart. This proof of principle demonstration shows how electrocardiogram measurements from embryonic zebrafish may become accessible by using electric field detection. We present preliminary results using the prototype, which enables the acquisition of electrophysiological signals from in vivo 3 and 5 days-post-fertilization zebrafish embryos. The recorded waveforms show electrocardiogram traces including detailed features such as QRS complex, P and T waves.
History
Publication status
- Published
Journal
Applied Physics LettersISSN
0003-6951Publisher
American Institute of PhysicsExternal DOI
Issue
19Volume
107Page range
1-4Article number
a193701Department affiliated with
- Informatics Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-10-28First Compliant Deposit (FCD) Date
2015-10-28Usage metrics
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