Depression and disability in people with podoconiosis: a comparative cross-sectional study in rural Northern Ethiopia

Bartlett, Joanna, Deribe, Kebede, Tamiru, Abreham, Amberbir, Tsige, Medhin, Girmay, Malik, Muzaffar, Hanlon, Charlotte and Davey, Gail (2016) Depression and disability in people with podoconiosis: a comparative cross-sectional study in rural Northern Ethiopia. International Health, 8 (2). pp. 124-131. ISSN 1876-3413

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Little is known about depressive symptoms in podoconiosis despite the independent contribution of depression to worse health outcomes and disability in people with other chronic disorders.


Two-hundred and seventy-one individuals with podoconiosis and 268 healthy neighbours (individuals from the nearest household in any direction) were investigated for depressive symptoms using a validated Amharic version of the Patient Health Questionnaire (PHQ-9). The WHO Disability Assessment Schedule II (WHODAS II) tool was used to measure disability. Logistic regression and zero inflated negative binomial regression were used to identify factors associated with elevated depressive symptoms, and disability, respectively.


Among study participants with podoconiosis, 12.6% (34/269) had high levels of depressive symptoms (scoring 5 or more points on the PHQ-9, on two assessments two weeks apart) compared to 0.7% (2/268) of healthy neighbours (p<0.001). Having podoconiosis and being older were significantly associated with increased odds of a high PHQ-9 score (adjusted odds ratios [AOR] 11.42; 95% CI 2.44-53.44 and AOR 1.04; 95% CI 1.00-1.08, respectively). Significant predictors of a higher disability score were having podoconiosis (WHODAS II multiplier value: 1.48; 95% CI 1.39-1.58) and having a high PHQ-9 score (1.07; 95% CI 1.06-1.08).


We recommend integrating evidence-based treatments for depression into podoconiosis interventions.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Global Health and Infection
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine > RA0773 Personal health and hygiene Including clothing, bathing, exercise, travel, nutrition, sleep, sex hygiene
Depositing User: Ellen Thomas
Date Deposited: 18 Aug 2015 11:27
Last Modified: 02 Jul 2019 14:35

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