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Depression and disability in people with podoconiosis: a comparative cross-sectional study in rural Northern Ethiopia

journal contribution
posted on 2023-06-08, 22:07 authored by Joanna Bartlett, Kebede Kassaye, Abreham Tamiru, Tsige Amberbir, Girmay Medhin, Muzaffar Malik, Charlotte Hanlon, Gail DaveyGail Davey
BACKGROUND Little is known about depressive symptoms in podoconiosis despite the independent contribution of depression to worse health outcomes and disability in people with other chronic disorders. METHOD Two-hundred and seventy-one individuals with podoconiosis and 268 healthy neighbours (individuals from the nearest household in any direction) were investigated for depressive symptoms using a validated Amharic version of the Patient Health Questionnaire (PHQ-9). The WHO Disability Assessment Schedule II (WHODAS II) tool was used to measure disability. Logistic regression and zero inflated negative binomial regression were used to identify factors associated with elevated depressive symptoms, and disability, respectively. RESULTS Among study participants with podoconiosis, 12.6% (34/269) had high levels of depressive symptoms (scoring 5 or more points on the PHQ-9, on two assessments two weeks apart) compared to 0.7% (2/268) of healthy neighbours (p<0.001). Having podoconiosis and being older were significantly associated with increased odds of a high PHQ-9 score (adjusted odds ratios [AOR] 11.42; 95% CI 2.44-53.44 and AOR 1.04; 95% CI 1.00-1.08, respectively). Significant predictors of a higher disability score were having podoconiosis (WHODAS II multiplier value: 1.48; 95% CI 1.39-1.58) and having a high PHQ-9 score (1.07; 95% CI 1.06-1.08). CONCLUSION We recommend integrating evidence-based treatments for depression into podoconiosis interventions.

History

Publication status

  • Published

File Version

  • Published version

Journal

International Health

ISSN

1876-3413

Publisher

Oxford University Press

Issue

2

Volume

8

Page range

124-131

Department affiliated with

  • Global Health and Infection Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-08-18

First Open Access (FOA) Date

2017-11-24

First Compliant Deposit (FCD) Date

2017-11-24

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