University of Sussex
Browse

File(s) not publicly available

Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin

journal contribution
posted on 2023-06-08, 21:27 authored by Sonja Wolff, Martin Stöter, Georgios GiamasGeorgios Giamas, Matthias Piesche, Doris Henne-Bruns, George Banting, Uwe Knippschild
In this study we identified snapin as an interaction partner of the CK1 isoform delta (CK1delta) in the yeast two-hybrid system and localized the interacting domains of both proteins. The interaction of CK1delta with snapin was confirmed by co-immunoprecipitation. Snapin was phosphorylated by CK1delta in vitro. Both proteins localized in close proximity in the perinuclear region, wherein snapin was found to associate with membranes of the Golgi apparatus. The identification of snapin as a new substrate of CK1delta points towards a possible function for CK1delta in modulating snapin specific functions.

History

Publication status

  • Published

Journal

FEBS Letters

ISSN

0014-5793

Publisher

Elsevier

Issue

27

Volume

580

Page range

6477-6484

Department affiliated with

  • Biochemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-07-07

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC