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OPTH-27083-keratoprostheses-for-corneal-blindness--a-brief-review-of-co_041615.pdf (9.14 MB)

Keratoprostheses for corneal blindness: a review of contemporary devices

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journal contribution
posted on 2023-06-08, 20:35 authored by Venkata Avadhanam, Helen Smith, Christopher Liu
According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases that produce corneal neovascularization, dry ocular surface and recurrent inflammation, or infections. A keratoprosthesis or KPro is the only alternative to restore vision when corneal graft is a doomed failure. Although a number of KPros have been proposed, only two devices, Boston type-1 KPro and osteo-odonto-KPro, have came to the fore. The former is totally synthetic and the latter is semi-biological in constitution. These two KPros have different surgical techniques and indications. Keratoprosthetic surgery is complex and should only be undertaken in specialized centers, where expertise, multidisciplinary teams, and resources are available. In this article, we briefly discuss some of the prominent historical KPros and contemporary devices.

History

Publication status

  • Published

File Version

  • Published version

Journal

Clinical Ophthalmology

ISSN

1177-5483

Publisher

Dove Medical Press

Volume

9

Page range

697-720

Department affiliated with

  • BSMS Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2015-04-24

First Open Access (FOA) Date

2015-04-24

First Compliant Deposit (FCD) Date

2015-04-24

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