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Urinary excretion of some purine bases in normal and schizophrenic subjects
journal contribution
posted on 2023-06-08, 20:07 authored by D A Booth, E B O Smith1. Ingestion of phenothiazine drugs did not detectably disturb the urinary excretion of purine bases by normal subjects. No significant differences in purine excretion were found between groups of normal subjects matched with schizophrenic patients untreated with phenothiazine drugs. Drug treatment had thus not obscured differences between normal and schizophrenic populations in a previous study, and conclusions drawn then were supported. 2. Excretion of 3-methylxanthine was more frequently detected among schizophrenic patients than among normal subjects, and this fact was probably attributable to increased ingestion of cocoa products by some patients. 3. Variations and correlations among the daily urinary excretions of endogenous and dietary purine bases are collated.
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Publication status
- Published
Journal
British Journal of PsychiatryISSN
0007-1250Publisher
Royal College of PsychiatristsExternal DOI
Issue
467Volume
110Page range
582-587Department affiliated with
- Psychology Publications
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- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-02-23Usage metrics
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