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5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylinositol 3 kinase enzymes (pi3) for the treatment of inflammatory airway diseases

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posted on 2023-06-08, 19:51 authored by Graham Charles Bloomfield, Ian Bruce, Judy Fox Hayler, Catherine Leblanc, Darren Le Grand, Clive McCarthy
Compounds of Formula (I) in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase such as inflammatory airway diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

History

Publication status

  • Published

Journal

FEBS Letters

Publisher

Elsevier

Volume

588

Page range

2874-2880

Department affiliated with

  • Chemistry Publications

Full text available

  • No

Legacy Posted Date

2015-06-02

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