Jouyban, Abolghasem, Shokri, Javad, Barzegar-Jalali, Mohammad, Hassanzadeh, Davoud, Acree Jr, William E, Ghafourian, Taravat and Nokhodchi, Ali (2010) Solubility of benzodiazepines in polyethylene glycol 200 + water mixtures at 303.2 K. Journal of Chemical and Engineering Data, 55 (1). pp. 519-522. ISSN 0021-9568
Full text not available from this repository.Abstract
Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban-Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban-Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version. © 2010 American Chemical Society.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Chemistry |
Subjects: | Q Science > QD Chemistry |
Depositing User: | Tom Gittoes |
Date Deposited: | 18 Dec 2014 14:56 |
Last Modified: | 30 Nov 2017 11:31 |
URI: | http://sro.sussex.ac.uk/id/eprint/51809 |