Dynamic construction of a coherent attentional state in a prefrontal cell population

Kadohisa, Mikiko, Petrov, Philippe, Stokes, Mark, Sigala, Natasha, Buckley, Mark, Gaffan, David, Kusunoki, Makoto and Duncan, John (2013) Dynamic construction of a coherent attentional state in a prefrontal cell population. Neuron, 80 (1). pp. 235-246. ISSN 0896-6273

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Prefrontal cortex has been proposed to show highly adaptive information coding, with neurons dynamically allocated to processing task-relevant information. To track this dynamic allocation in monkey prefrontal cortex, we used time-resolved measures of neural population activity in a simple case of competition between target (behaviorally critical) and nontarget objects in opposite visual hemifields. Early in processing, there were parallel responses to competing inputs, with neurons in each hemisphere dominated by the contralateral stimulus. Later, the nontarget lost control of neural activity, with emerging global control by the behaviorally critical target. The speed of transition reflected the competitive weights of different display elements, occurring most rapidly when relative behavioral significance was well established by training history. In line with adaptive coding, the results show widespread reallocation of prefrontal processing resources as an attentional focus is established.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine
Depositing User: Lene Hyltoft
Date Deposited: 18 Sep 2013 07:33
Last Modified: 27 Jul 2017 18:27
URI: http://sro.sussex.ac.uk/id/eprint/46314
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