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The EuroSIDA study: Regional differences in the HIV-1 epidemic and treatment response to antiretroviral therapy among HIV-infected patients across Europe--a review of published results

journal contribution
posted on 2023-06-08, 15:20 authored by Daria Podlekareva, Wendy Bannister, Amanda Mocroft, Ludmila Abrosimova, Igor Karpov, Jens D Lundgren, Ole Kirk, Martin Fisher, The EuroSIDA Study Group
EuroSIDA is a pan-European observational study that follows 14,265 HIV-infected patients from 31 European countries, Israel and Argentina, of which 2,560 are patients from eastern Europe (EE). The study group has performed several analyses addressing regional differences in the HIV-epidemic across Europe, where all countries were divided into five regions: south, west central, north, east central Europe and EE. Significant regional differences in patients' characteristics and pattern of AIDS diagnoses were documented. More patients from EE were diagnosed with tuberculosis compared to other regions. Significantly fewer HIV-infected patients in EE, who fulfilled the criteria for starting combination antiretroviral therapy (cART), actually received cART as compared with other regions of Europe. Those, receiving cART in EE had a lower initial virologic response rate irrespectively of the regimen used, although it has improved within years. Besides, treatment failure was more common in this region. Thus, improvements in the clinical management of HIV patients in EE are urgently needed. Strategies include creating scientific collaborations for HIV clinicians as well as teaching clinicians about the most advanced HIV management at clinically oriented courses held in eastern Europe.

History

Publication status

  • Published

Journal

Central European Journal of Public Health

ISSN

1210-7778

Publisher

National Institute of Public Health

Issue

3

Volume

16

Page range

99-105

Department affiliated with

  • BSMS Publications

Notes

Martin Fisher is not listed as a main author in the citation but forms part of the EuroSIDA Study Group

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2013-08-05

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