Venkataraman_CMBE15_Abstract.pdf (2.35 MB)
Modelling and simulation of cell migration in heterogeneous media
conference contribution
posted on 2023-06-08, 15:20 authored by Charles Martin Elliott, Bjorn Stinner, Vanessa StylesVanessa Styles, Chandrasekhar VenkataramanChandrasekhar VenkataramanCell motility is a complex process comprising, among others, cytoskeletal remodelling and growth, active force generation, chemical transport and reaction of multiple substances inside and outside the cell as well as on the cell membrane, anisotropic material behavior of the cell and of the extracellular matrix (ECM), and proteolytic cleavage of the ECM. We are working on an evolving finite element based computational framework that is able to incorporate models and methods for all the key features of cell motility. The approach exploits a mesoscopic point of view and aims at a comprehensive 3D model allowing for the simulation of cell motility at reasonable computational costs. In the presentation we will first sketch the overall framework, addressing all the respective models and methods, and will then focus on some essential subunits.
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Publication status
- Published
File Version
- Accepted version
Journal
CMBE15: 4th International Conference on Computational & Mathematical Biomedical Engineering, 29th June - 1st July 2015 École Normale Supéerieure de Cachan, Cachan (Paris) FrancePublisher
CMBEPublisher URL
Page range
401-404Pages
867.0Event name
4th International Conference Computational & Mathematical Biomedical EngineeringEvent location
Paris, FranceEvent type
conferenceEvent date
29 June - 01 July, 2015Book title
CMBE15: 4th International Conference on Computational & Mathematical Biomedical Engineering, 29th June - 1st July 2015 École Normale Supéerieure de Cachan, Cachan (Paris) FrancePlace of publication
Swansea, UKISBN
9780956291431Department affiliated with
- Mathematics Publications
Full text available
- Yes
Peer reviewed?
- Yes
Editors
Perumal Nithiarasu, Elisa BudynLegacy Posted Date
2015-11-24First Open Access (FOA) Date
2015-11-24First Compliant Deposit (FCD) Date
2015-11-24Usage metrics
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