File(s) not publicly available
Spikes and ribbon synapses in early vision
journal contribution
posted on 2023-06-08, 15:14 authored by Tom Baden, Thomas Euler, Matti Weckstrom, Leon LagnadoLeon LagnadoImage processing begins in the retina, where neurons respond with graded voltage changes that must be converted into spikes. This conversion from 'analog' to 'digital' coding is a fundamental transformation carried out by the visual system, but the mechanisms are still not well understood. Recent work demonstrates that, in vertebrates, graded-to-spiking conversion of the visual signal begins in the axonal system of bipolar cells (BCs), which transmit visual information through ribbon-type synapses specialized for responding to graded voltage signals. Here, we explore the evidence for and against the idea that ribbon synapses also transmit digital information. We then discuss the potential costs and benefits of digitization at different stages of visual pathways in vertebrates and invertebrates.
History
Publication status
- Published
Journal
Trends in NeurosciencesISSN
0166-2236Publisher
ElsevierExternal DOI
Issue
8Volume
36Page range
480-488Department affiliated with
- Neuroscience Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2013-06-19Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC