File(s) not publicly available
Changes in plasma level of heat shock protein 27 after acute coronary syndrome
journal contribution
posted on 2023-06-08, 13:46 authored by Ali Reza Heidari-Bakavoli, Amirhossein Sahebkar, Naser Mobara, Mohsen Moohebati, Shima Tavallaie, Amir Ali Rahsepar, Abolfazl Kazemi, Maryam-Sadat Alavi, Majid Ghayour-Mobarhan, Gordon FernsGordon FernsWe assessed the association between serum heat shock protein 27 (Hsp-27)concentrations in patients with acute coronary syndrome (ACS) and compared them with healthy participants. Patients with ACS (n = 75) were recruited and their biochemical parameters were compared with 75 healthy participants. Heat shock protein 27 concentrations were measured from blood samples taken on admission and 12 hours after the onset of chest pain. In the patient group, Hsp-27 concentrations (31.62 [20.12-38.51] ng/mL) in the first blood samples were significantly (P < .001) higher than in control samples (20.12 [16.67-28.17] ng/mL). In patients, serum Hsp-27 levels on admission were significantly (P < .001) higher than for the samples collected 12 hours after the onset of chest pain (25.87 [15.52-31.62]); the latter did not differ significantly from samples of healthy controls. In conclusion, serum Hsp-27 concentrations are elevated in the early hours following ACS, but fall to levels near to those in healthy individuals after about 12 hours from the onset of chest pain.
History
Publication status
- Published
Journal
AngiologyISSN
1940-1574External DOI
Issue
1Volume
63Page range
12-16Department affiliated with
- Division of Medical Education Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-11-19Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC