Darbandi, Mahsa, Darbandi, Sara, Mobarhan, Majid Ghayor, Owji, Ali Akbar, Zhao, Baxiao, Iraji, Kambiz, Abdi, Hamid, Saberfiroozi, Mehdi, Nematy, Mohsen, Safarian, Mohammad, Parizadeh, Mohammad Reza, Abbasi, Parisa, Salehmoghadam, Masoud, Fardaei, Majid, Dabbaghmanesh, Mohammad Hossein, Ferns, Gordon and Mokarram, Pooneh (2012) Effects of auricular acupressure combined with low-calorie diet on the leptin hormone in obese and overweight Iranian individuals. Acupuncture in medicine : journal of the British Medical Acupuncture Society, 30 (3). pp. 208-213. ISSN 1759-9873

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Abstract

BACKGROUND

Human leptin is a peptide hormone that is released from white adipocytes. The absence of leptin or its receptor leads to uncontrolled food intake, leading to obesity. In the present work, the effects of auricular acupressure combined with low-calorie diet on the leptin hormone level were investigated.

METHODS

Volunteers (n=86) with body mass indices (BMI) between 25 and 45 kg/m² were randomised into a case (n=43) or a control (n=43) group. Participants in each group received a low-calorie diet for 6 weeks. The case group was treated with auricular acupressure and the control group received a sham procedure. Plasma leptin levels, body fat mass, body weight and BMI were measured before and after treatment.

RESULTS

Participants who received auricular acupressure showed significant reductions in their plasma leptin levels (18.57%, p<0.01) as well as in their body fat mass (4%, p<0.05). These changes were not observed in the control group. The reduction in leptin was significantly greater in the acupressure group than the controls.

CONCLUSIONS

Auricular acupressure combined with a low-calorie diet significantly reduced plasma levels of leptin. However, the mechanism of this reduction is not clear.

Item Type:	Article
Schools and Departments:	Brighton and Sussex Medical School > Division of Medical Education
Subjects:	R Medicine > R Medicine (General) > R735 Medical education
Depositing User:	Gordon Ferns
Date Deposited:	16 Nov 2012 15:13
Last Modified:	16 Nov 2012 15:13
URI:	http://sro.sussex.ac.uk/id/eprint/42628

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