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Absence of close-facing retrotransposons: A comparison of molecular data and theory
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posted on 2023-06-08, 10:40 authored by Alexandros BousiosAlexandros Bousios, David Waxman, Stephen R PearceRetrotransposons occur in extremely large numbers in many eukaryotic genomes. However, little is known of the factors which affect the distribution of close proximity retrotransposons. In this work we investigate the frequency of close facing retrotransposons in a plant species with extremely high numbers of retrotransposons. Molecular observations are compared with predictions of a mathematical model that assumes a uniform probability of retrotransposon insertion into the genome. The mathematical model plays the role of a null hypothesis. We find that compared with the predictions of the model, there is a statistically significant deficit of identical copies of facing retroelements that are close to one another. This suggests that an efficient mechanism exists that removes or limits close facing retroelements.
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Publication status
- Published
Journal
Journal of Theoretical BiologyISSN
0022-5193External DOI
Issue
2Volume
364Page range
205-210Pages
6.0Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-21Usage metrics
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