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Absence of close-facing retrotransposons: A comparison of molecular data and theory

journal contribution
posted on 2023-06-08, 10:40 authored by Alexandros BousiosAlexandros Bousios, David Waxman, Stephen R Pearce
Retrotransposons occur in extremely large numbers in many eukaryotic genomes. However, little is known of the factors which affect the distribution of close proximity retrotransposons. In this work we investigate the frequency of close facing retrotransposons in a plant species with extremely high numbers of retrotransposons. Molecular observations are compared with predictions of a mathematical model that assumes a uniform probability of retrotransposon insertion into the genome. The mathematical model plays the role of a null hypothesis. We find that compared with the predictions of the model, there is a statistically significant deficit of identical copies of facing retroelements that are close to one another. This suggests that an efficient mechanism exists that removes or limits close facing retroelements.

History

Publication status

  • Published

Journal

Journal of Theoretical Biology

ISSN

0022-5193

Issue

2

Volume

364

Page range

205-210

Pages

6.0

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-21

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