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Response to Kondrashov
journal contribution
posted on 2023-06-08, 09:48 authored by Peter D Keightley, Adam Eyre-WalkerAdam Eyre-WalkerThe 'mutational deterministic' hypothesis proposes that a high genomic rate of deleterious mutation (U) might maintain sexual reproduction. Our recent work casts doubt on this, as we estimate a low U for sexually reproducing species with short generation times. Following criticism by Kondrashov, here we defend our methods for estimating U and challenge the mutational deterministic hypothesis.
History
Publication status
- Published
Journal
Trends in GeneticsISSN
0168-9479Issue
2Volume
17Page range
77-88Pages
12.0Department affiliated with
- Evolution, Behaviour and Environment Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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