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Response to Kondrashov

journal contribution
posted on 2023-06-08, 09:48 authored by Peter D Keightley, Adam Eyre-WalkerAdam Eyre-Walker
The 'mutational deterministic' hypothesis proposes that a high genomic rate of deleterious mutation (U) might maintain sexual reproduction. Our recent work casts doubt on this, as we estimate a low U for sexually reproducing species with short generation times. Following criticism by Kondrashov, here we defend our methods for estimating U and challenge the mutational deterministic hypothesis.

History

Publication status

  • Published

Journal

Trends in Genetics

ISSN

0168-9479

Issue

2

Volume

17

Page range

77-88

Pages

12.0

Department affiliated with

  • Evolution, Behaviour and Environment Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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