Keightley, Peter D and Eyre-Walker, Adam (2001) Response to Kondrashov. Trends in Genetics, 17 (2). pp. 77-88. ISSN 0168-9479

Full text not available from this repository.

Abstract

The 'mutational deterministic' hypothesis proposes that a high genomic rate of deleterious mutation (U) might maintain sexual reproduction. Our recent work casts doubt on this, as we estimate a low U for sexually reproducing species with short generation times. Following criticism by Kondrashov, here we defend our methods for estimating U and challenge the mutational deterministic hypothesis.

Item Type:	Article
Schools and Departments:	School of Life Sciences > Evolution, Behaviour and Environment
Depositing User:	Adam Eyre-Walker
Date Deposited:	06 Feb 2012 21:22
Last Modified:	22 Mar 2012 15:43
URI:	http://sro.sussex.ac.uk/id/eprint/30967

📧 Request an update