Response to Kondrashov

Keightley, Peter D and Eyre-Walker, Adam (2001) Response to Kondrashov. Trends in Genetics, 17 (2). pp. 77-88. ISSN 0168-9479

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The 'mutational deterministic' hypothesis proposes that a high genomic rate of deleterious mutation (U) might maintain sexual reproduction. Our recent work casts doubt on this, as we estimate a low U for sexually reproducing species with short generation times. Following criticism by Kondrashov, here we defend our methods for estimating U and challenge the mutational deterministic hypothesis.

Item Type: Article
Schools and Departments: School of Life Sciences > Evolution, Behaviour and Environment
Depositing User: Adam Eyre-Walker
Date Deposited: 06 Feb 2012 21:22
Last Modified: 22 Mar 2012 15:43
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