Ateh, D, Hussain, I, Mustafa, A, Price, K M, Nickols, C D, Bird, M M, Greensmith, L, Schiavo, G, Hafezparast, M, Fisher, E M C, Baker, C S and Martin, J E (2006) Subcellular functional specificity of dynein-dynactin complex subunits - normal distribution and disturbances in neurodegenerative disease. Journal of Pathology, 208 (S1). 23A-23A. ISSN 0022-3417
Full text not available from this repository.Abstract
Cytoplasmic dynein and its activating complex dynactin drive the retrograde transport of material necessary for the survival and proper functioning of neurons. Disruption of the dynein-dynactin complex by either over-expression of the dynamitin subunit or by mutations within individual dynein/dynactin subunits can cause motor neuron degeneration.
Item Type: | Article |
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Additional Information: | 189th Meeting of the Pathological Society of Great Britain and Ireland. Robinson College, Cambridge. 4-6th January, 2006 |
Schools and Departments: | School of Life Sciences > Neuroscience |
Depositing User: | EPrints Services |
Date Deposited: | 06 Feb 2012 21:13 |
Last Modified: | 02 Jul 2012 14:18 |
URI: | http://sro.sussex.ac.uk/id/eprint/30309 |