Rogers, Derek C, Peters, Jo, Martin, Joanne E, Ball, Simon, Nicholson, Sharon J, Witherden, Abi S, Hafezparast, Majid, Latcham, Judy, Robinson, Tracey L, Quilter, Charlotte A and Fisher, Elizabeth M C (2001) SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. Neuroscience Letters, 306 (1-2). pp. 89-92. ISSN 0304-3940

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Abstract

Mouse models of neurological abnormalities are only valuable if accurately assessed. The three-stage SHIRPA procedure is used for the standardised assessment of mouse phenotype and has been reported in a high throughput experiment in which different mutants were ascertained at one age point using stage 1 of the protocol. In this study we have validated SHIRPA using a large cohort with one single mutation, 'legs at odd angles that causes neurological dysfunction. The cohort aged from 1 to 16 months during this study and this is the first longitudinal SHIRPA analysis.

Item Type:	Article
Schools and Departments:	School of Life Sciences > Neuroscience
Depositing User:	Majid Hafezparast
Date Deposited:	06 Feb 2012 21:11
Last Modified:	26 Mar 2012 14:04
URI:	http://sro.sussex.ac.uk/id/eprint/30105

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