Rogers, Derek C, Peters, Jo, Martin, Joanne E, Ball, Simon, Nicholson, Sharon J, Witherden, Abi S, Hafezparast, Majid, Latcham, Judy, Robinson, Tracey L, Quilter, Charlotte A and Fisher, Elizabeth M C (2001) SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice. Neuroscience Letters, 306 (1-2). pp. 89-92. ISSN 0304-3940
Full text not available from this repository.Abstract
Mouse models of neurological abnormalities are only valuable if accurately assessed. The three-stage SHIRPA procedure is used for the standardised assessment of mouse phenotype and has been reported in a high throughput experiment in which different mutants were ascertained at one age point using stage 1 of the protocol. In this study we have validated SHIRPA using a large cohort with one single mutation, 'legs at odd angles that causes neurological dysfunction. The cohort aged from 1 to 16 months during this study and this is the first longitudinal SHIRPA analysis.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Neuroscience |
Depositing User: | Majid Hafezparast |
Date Deposited: | 06 Feb 2012 21:11 |
Last Modified: | 26 Mar 2012 14:04 |
URI: | http://sro.sussex.ac.uk/id/eprint/30105 |