Methimazole-Based Ionic Liquids

Siriwardana, Amal I, Crossley, Ian R, Torriero, Angel A J, Burgar, Iko M, Dunlop, Noel F, Bond, Alan M, Deacon, Glen B and MacFarlane, Douglas R (2008) Methimazole-Based Ionic Liquids. The Journal of Organic Chemistry, 73 (12). pp. 4676-4679. ISSN 0022-3263

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The alkylation reaction of 2-mercapto-1-methylimidazole 1a with iodoethane and chlorobutane produced S-alkylmethimazole halides 2a and 2b which were subjected to anion metathesis with two different metal salts (MA) to afford methimazole-based room-temperature ionic liquids 3a, 3b, and 3c in 82%, 85%, and 87% yields, respectively. S-Alkylation giving 2a and 2b suggests that methimazole reacts through the thione tautomer.

Item Type: Article
Additional Information: 'second author' two other experimentalists. IMB, NFD, AMB, GBD, DRM all 'management team'
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Ian Crossley
Date Deposited: 06 Feb 2012 21:08
Last Modified: 24 Jul 2013 11:34
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