Roch, Fernando, Alonso, Claudio R and Akam, Michael (2003) The Drosophila miniature and dusky encode ZP-proteins required for cytoskeletal reorganisation during wing morphogenesis. Journal of Cell Science, 116 (7). pp. 1199-1207. ISSN 0021-9533

Full text not available from this repository.

Abstract

We have characterised the function of two Drosophila genes, miniature and dusky, that are required for the morphological reorganisation of the apical membrane during wing epidermis differentiation. These genes encode transmembrane proteins containing a ZP (zona pellucida) domain and are homologous to several vertebrate and invertebrate apical matrix components. miniature and dusky are only expressed in tissues secreting a cuticle, and the Min protein localises to the apical membrane during the early stages of cuticle formation. We propose that Min and Dusky form a novel subfamily within the ZP domain proteins and are specifically involved in the interactions between the apical membrane, the cytoskeleton and the forming cuticle.

Item Type:	Article
Additional Information:	I described a new family of ZP-proteins and their roles during the changes in cell morphology that lead to fly wing differentiation
Schools and Departments:	School of Life Sciences > Evolution, Behaviour and Environment
Depositing User:	Claudio Alonso
Date Deposited:	06 Feb 2012 20:52
Last Modified:	22 Mar 2012 12:27
URI:	http://sro.sussex.ac.uk/id/eprint/28502

📧 Request an update