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Normalization for sparse encoding of odors by a wide-field interneuron
journal contribution
posted on 2023-06-08, 00:32 authored by Maria Papadopoulou, Stijn Cassenaer, Thomas NowotnyThomas Nowotny, Gilles LaurentSparse coding presents practical advantages for sensory representations and memory storage. In the insect olfactory system, the representation of general odors is dense in the antennal lobes but sparse in the mushroom bodies, only one synapse downstream. In locusts, this transformation relies on the oscillatory structure of antennal lobe output, feed-forward inhibitory circuits, intrinsic properties of mushroom body neurons, and connectivity between antennal lobe and mushroom bodies. Here we show the existence of a normalizing negative-feedback loop within the mushroom body to maintain sparse output over a wide range of input conditions. This loop consists of an identifiable "giant" nonspiking inhibitory interneuron with ubiquitous connectivity and graded release properties.
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Publication status
- Published
Journal
ScienceISSN
0036-8075Publisher
American Association for the Advancement of ScienceExternal DOI
Issue
6030Volume
332Page range
721-725Department affiliated with
- Informatics Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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