Studies on Pd/imidazolium salt protocols for aminations of aryl bromides and iodides using lithium hexamethyldisilazide (LHMDS)

Lerma, Israel Conesa, Cawley, Mark J, Cloke, F Geoffrey N, Arentsen, Katherine, Scott, James S, Pearson, Stuart E, Hayler, John and Caddick, Stephen (2005) Studies on Pd/imidazolium salt protocols for aminations of aryl bromides and iodides using lithium hexamethyldisilazide (LHMDS). Journal of Organometallic Chemistry, 690 (24). pp. 5841-5848. ISSN 0022328X

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Abstract

The reactions of a range of secondary amines with aryl bromides and iodides have been performed using an in situ protocol involving palladium and imidazolium salts. Many of these reactions proceed at room temperature, providing a mild protocol for aminations of aryl iodides and bromides. Key to the success of this procedure is the use of lithium hexamethyldisilazide (LHMDS) as base.

Item Type: Article
Additional Information: Pearson, S E. Hayler, J. Caddick, S.
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Geoff Cloke
Date Deposited: 06 Feb 2012 19:54
Last Modified: 30 Nov 2012 17:05
URI: http://sro.sussex.ac.uk/id/eprint/22925
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