Evolutionary genomics: reading the bands

Hurst, Laurence D and Eyre-Walker, Adam (2000) Evolutionary genomics: reading the bands. BioEssays, 22 (2). pp. 105-107. ISSN 0265-9247

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The human genome is not a uniform structure but, instead, is a mosaic of bands. Some of these bands can be seen by the eye. Stained with Giemsa and viewed under the microscope each human chromosome has a prototypical pattern of light and dark bands (G and R bands respectively). Other bands are not so easily viewed. The human genome is, for example, a mosaic of isochores, blocks of DNA within which the proportion of the bases G and C at silent sites (introns, third positions in codons, intergene spacer) is fairly uniform. Recent work by Matassi and colleagues(1) has revealed what might be a new and unexpected banding pattern. They have found that the genes which are close together on the chromosome have similar rates of evolution. BioEssays 22:105¿107, 2000. ©2000 John Wiley & Sons, Inc.

Item Type: Article
Schools and Departments: School of Life Sciences > Evolution, Behaviour and Environment
Depositing User: Adam Eyre-Walker
Date Deposited: 06 Feb 2012 19:51
Last Modified: 21 Mar 2012 10:44
URI: http://sro.sussex.ac.uk/id/eprint/22600
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