Lukashkin, Andrei N, Bashtanov, Mikhail E and Russell, Ian J (2005) A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea. Journal of Neuroscience Methods, 148 (2). pp. 122-129. ISSN 0165-0270

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Abstract

A laser-diode forms the basis of a displacement sensitive homodyne interferometer suitable for measurements from poorly reflective surfaces. The compact and cost-effective interferometer utilizes the self-mixing effect when laser light reflected from a moving target re-enters the laser cavity and causes phase dependent changes of the lasing intensity. A piezo positioner was used to displace the interferometer with known frequency and amplitude as a basis for real-time calibration of the interferometer's sensitivity. The signal-processing algorithm is described that allows measurements in presence of high amplitude noise leading to variation of the interferometer's operating point. Measurements of sound-induced basilar membrane displacements were made in the intact cochleae of rodents by focusing the laser beam of the interferometer through the transparent round window membrane. The interferometer provides a viable means for making subnanometre mechanical measurements from structures in the inner ears of small mammals, where opening of the cochlea is not practicable.

Item Type:	Article
Additional Information:	Principal author
Schools and Departments:	School of Life Sciences > Biology and Environmental Science
Depositing User:	Andrei Lukashkin
Date Deposited:	06 Feb 2012 19:51
Last Modified:	21 Mar 2012 09:51
URI:	http://sro.sussex.ac.uk/id/eprint/22532

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